Emolisi in vivo. Parte I: classificazione

AUTORI

ABSTRACT

In vivo hemolysis. Part I: classification

Hemolytic anemias are characterized by a reduction of the average life span of red blood cells. In some cases, the hemolysis may be massive, thus representing a life-threatening condition, which management is challenging for physicians. In other cases, hemolysis may be compensated by bone marrow stimulation or became overt only in particular conditions. From an etiologic point of view, hemolytic anemias can be divided in congenital and acquired forms. Inherited hemolytic anemias are usually diagnosed in the childhood and are due to intracorpuscolar defects (with the exception of paroxysmal nocturnal hemoglobinuria), while acquired hemolytic anemias are mainly extracorpuscolar. The prompt recognition of symptoms and a correct differential diagnosis are essential to establish a correct therapeutic approach.

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