Aggiornate le linee guida dell’American Association of Clinical Chemistry sul ruolo del Laboratorio Analisi nella diagnosi e nel monitoraggio del Diabete Mellito

AUTORI

ABSTRACT

Latest update on the American Association of Clinical Chemistry guidelines for laboratory diagnosis and management of diabetes mellitus

In this short document we propose an update on the latest AACC 2023 standards for the diagnosis and monitoring of diabetes at the laboratory level. In particular we will focus on some recommendations expressed in relation to the measurement of blood glucose, both with laboratory methods and through systems for continuous blood glucose monitoring, on the measurement of glycated hemoglobin and other glycated proteins, in particular glycated albumin. Some statements relating to the diagnosis of gestational diabetes, the measurement of ketone bodies, autoantibodies and C-peptide will also be considered. Particular attention is given to the quantitative measurement of albumin in urine.

BIBLIOGRAFIA

1. BIBLIOGRAFIA
2. Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2002;48:436-72.
3. 1706 citazioni su PubMed https://pubmed.ncbi.nim.nih.gov/11861436 (ultimo accesso: gennaio 2024).
4. Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2011;57:e1–47.
5. Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Lernmark Å, et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2023;69:808-68.
6. Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Lernmark Å, et al. Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2023;69:777-84.
7. Kilpatrick ES. New laboratory guidelines for diabetes: continuing the collaboration between clinical and laboratory medicine. Clin Chem 2023;69:785-7.
8. Bonetti G, Carta M, Lapolla A, Miccoli R, Testa R, Mosca A. Raccomandazioni per l’ottimizzazione della fase pre-analitica per una corretta determinazione della glicemia in ambito diabetologico. Biochim Clin 2018;42:263-5.
9. González-Lao E, Corte Z, Simón M, Ricós C, Coskun A, Braga F et al. Systematic review of the biological variation data diabetes releted analytes. Clin Chim Acta 2019;488:61-7.
10. Freckmann G, Nichols JH, Hinzmann R, Klonoff DC, Ju Y, Diem P, et al. Standardization process of continuous glucose monitoring: Traceability and performance. Clin Chim Acta 2021;515:5-12.
11. Eichenlaub M, Stephan P, Waldenmaier D, Pleus S, Rothenbühler M, Haug C,, et al. Continuous glucose deviation interval and variability analysis (CG-DIVA): a novel approach for the statistical accuracy assessment of continuous glucose monitoring systems. J Diabetes Sci Techol 2022; aop doi 10.1177/19322968221134639
12. Lapolla A, Mosca A. Screening e diagnosi del diabete gestazionale: definite le raccomandazioni. Biochim Clin 2012;36:12-4.
13. Mosca A. La determinazione dell’emoglobina glicata nel sangue umano: attualità e prospettive. Biochim Clin 2008;32:27-35.
14. Paleari R, Bonetti G, Callà C, Carta M, Ceriotti F, Di Gaetano N, et al. Multicenter evaluation of an enzymatic method for glycated albumin. Clin Chim Acta 2017;469:81-6.
15. Carta M Paleari R, Terreni A, Mosca A. How to report HbA1c in presence of hemoglobin variants. Biochim Clin 2022;46:176-9.
16. Weykamp C, John G, Gillery P, English E, Ji L, Lenters-Westra E, et al. Investigation of 2 Models to Set and Evaluate Quality Targets for Hb A1c: Biological Variation and Sigma-Metrics. Clin Chem 2015;61:752-9.
17. www.siditalia.it/clinica/standard-di-cura-amd-sid (ultimo accesso: gennaio 2024)
18. www.aemmedi.it/standard-di-cura/ (ultimo accesso: gennaio 2024).