English 
Italian CASI CLINICI – Case Reports
Volume:
Biochimica Clinica 2019; 43(2) e009-e011
Published on-line:
April 16, 2019
DOI:
10.19186/BC_2019.023
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Astenia e urine intensamente colorate: una associazione da indagare attentamente
AUTHORS
Valentino Granero12, Gianni Bourlot2, Angela D’Alessandro3, Elvio Peyronel2, Liliana Calosso3, Maria Rita Cavallo2
1Immunoematologia e Medicina Trasfusionale – Azienda Sanitaria Locale Asti
2Laboratorio Analisi Unificato Rivoli-Pinerolo ASL TO3, Pinerolo (TO).
3Servizio Trasfusionale Pinerolo Azienda Sanitaria Locale TO3, Pinerolo (TO)
1Immunoematologia e Medicina Trasfusionale – Azienda Sanitaria Locale Asti
2Laboratorio Analisi Unificato Rivoli-Pinerolo ASL TO3, Pinerolo (TO).
3Servizio Trasfusionale Pinerolo Azienda Sanitaria Locale TO3, Pinerolo (TO)
ABSTRACT
Asthenia and extremely colored urine: an association to be investigated carefully
Autoimmune hemolyticanemia (AIHA) is a relatively rare disease where red blood cells are selectively destroyed by auto-antibodies. Ingeneral, direct antiglobulin test (DAT) is the test used for confirmation even if there are other markers to guide thedifferential diagnosis and to evaluate the degree of hemolysis. We present a case of severe warm-type AIHA occurredin a thirty-six year old man with initial symptoms of asthenia and dark urine. The case shows how specialists inlaboratory medicine can play a fundamental role in the diagnostic process through an appropriate use of the tests,speeding up the management of the patient, improving thus the prognosis.