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CASI CLINICI – Case Reports

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Biochimica Clinica 2014; 38(3) 268-271

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“Smart drugs”, le nuove droghe sul web: due casi di intossicazione acuta

AUTORI

Maria Concetta Rotolo, Manuela Pellegrini, Renata Solimini, Simona Pichini, Roberta Pacifici
Dipartimento del Farmaco, Istituto Superiore di Sanità

ABSTRACT

“Smart drugs”, the new drugs on the web: two cases of acute intoxication

New psychoactive substances that in some cases are not subjected to any legal restriction recently overwhelmed web market. They were historically defined “smart drugs”: substances either natural or synthetic with alleged psychoactive effects as well as effects on sexual performance. We present here two intoxication cases: the first concernes a male subject hospitalized for deep unconsciousness, who took in yohimbine and kawaine, two psychoactive alkaloids present in herbal preparations of Pausinystalia yohimbe and Piper methysticum, sold on the sexy shop websites; the second concernes a female with a previous history of drug poliabuse, hospitalized for dysphoric syndrome/hallucinations, who took in benzydamine, a local anesthetic and analgesic drug, contained in an antibacterial gynecological powder that in oral mis-overdosage acts as a deliriant and central nervous system stimulant.

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