Sistema POCT per la determinazione su sangue intero della troponina cardiaca I ad alta sensibilità: quale valore nel territorio?
POCT system for the determination of high sensitivity cardiac troponin I: the value in the territory
AUTORI
1 U.O.C. Medicina di Laboratorio, Azienda Ospedale – Università di Padova
2 QI.LAB.MED. Padova
ABSTRACT
POCT system for the determination of high sensitivity cardiac troponin I: the value in the territory
The Italian National Recovery and Resilience Plan (NRRP) provides resources for the activation for over a thousand Community Houses that will serve as permanent points of reference for the population with the aim to guarantee both the prevention activity and the care of patients. These structures need to be provided with Information Technology (essential for the implementation of telemedecine), an adequate multi-specialty instrumental equipment (radiology, clinical laboratory) and a multidisciplinary team of medical specialists, paediatricians, nurses and other health professionals. In this context, the clinical laboratory activity takes on a strategic role especially in the diagnosis of the acute miocardial damage (AMI) which is fundamentally based on the determination of Troponin I o T and no longer on instrumental investigations, such as ECG. High quality POCT devices are currently available on the market for the determination of Troponin I (and T) with high sensitivity methods characterized by adequate costs for the diagnostic efficacy they should guarantee. Recently, the POCT system QuidelTriage High Sensitivity Troponin I test has been evaluated using 75 whole blood samples from patients. Overall, the outcome of the trial was satisfactory and corresponded to the quality and performance specifications recommended by AACC and IFCC for a method that should assure an elevated level of diagnostic accuracy. The tested POCT device was effective in the management of patients with suspected AMI using either single cut-off value or 0/1 hour algorithm. This demonstrates the important contribution that POCT devices can offer for of early diagnosis and monitoring of chronic disease
